There are three forms of tianeptine on the market,they are Tianeptine Sodium Salt ,Tianeptine Acid and Tianpetine Sulfate. To know their differences,firstly you need to know why do so many medications appears as a salt form. A considerable proportion of drugs are organic acid or alkali salt, and often is a weak organic acid and strong inorganic base, weak organic base and strong inorganic acid salt. As a result of salt, so that some oil loaded organic acids or a few bases into a solid, is conducive to the preparation of some solid dosage forms; The salinization of drugs increases water solubility, which is beneficial to the preparation of some water-containing dosage forms, such as water injection and oral liquid. Into salt process, often also is a kind of purification process to remove the mixed cannot into salt impurities in the drug, but sometimes also can bring some problems worthy of note, for example, in the process of salt crystallization can adsorption and bag miscellaneous go into salt organic impurities (such as the reaction steps of raw materials or by-products), even if in the later recrystallization process is also difficult to completely remove them. At this point, it is necessary…
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