Nootropicsorigin as a long-time experienced supplier of phenibut hcl, we noticed that there are two kinds form of phenibut hcl on the market. Back to the resources side, the main manufacturers are three factories which we have been working with, two of the manufacturers are providing fine powder and the other pharmaceutical factory is providing crystal one mesh ranges 30mesh -100mesh. Crystal phenibut hcl and powder phenibut hcl essentially are all crystal just mesh differences.
After comparing to the COAs, we find data are not many differences no matter fine powder or crystal powder. Here we have arranged three batches of samples from different manufacturers. The main test items have been shown on the below sheet, we can see three samples all are approved of the standard data ranges, but crystal phenibut data is much close to the standard and is slightly better than the other two fine powder ones.
Among the test items, Specific Rotation is a new specification requested by one of the customers which pointed out Phenibut HCL has R and S differences. By researching the documents and consulting with the factory, we figured out phenibut hcl is R+S mixed enantiomers.
Phenibut is a chiral molecule and thus has two potential configurations, as (R)- and (S)-enantiomers. Most commercial phenibut is reported to be in the form of hydrochloride salt (HCl). In this form, the phenibut is reacted with hydrochloric acid to form a stable, easily dissolvable, acidic, crystalline salt. There is no single R or S enantiomer single existence. As a racemic mixture, the expected Specific Rotation is close to 0,in the actual test the standard is -0.1~+0.1. We can see crystal phenibut is closer to 0.
As for the cost, by our purchasing experience, powder form phenibut hcl costs more or less the same to crystal phenibut hcl depending on quantity differences. However we find one more advantage of crystal phenibut hcl is, it is more clean and easier to refill in capsules.
As for the affection, technically to say should be not much difference, under the same cost, personally, I think crystal phenibut hcl is much better. That’s why we Nootropicsorigin will just provide crystal Phenibut HCL in the future.