Palmitoylethanolamide (PEA) powder (Cas:544-31-0)

Palmitoylethanolamide (PEA) powder is an endogenous fatty acid amide. It is a weak ligand of the cannabinoid 1 (CB1) and cannabinoid 2 (CB2) receptors. Palmitoylethanolamide acts by binding to an unidentified cannabinoid receptor that is similar to CB2, exhibits anti-inflammatory, anti-nociceptive, neuroprotective, and anticonvulsant properties in vivo. Producing robust anti-inflammatory actions by activating PPARα, acts as a selective agonist for GPR55 receptors (EC50 = 4, 19 800 and > 30 000 nM at GPR55, CB2 and CB1 receptors respectively).

Specification: Palmitoylethanolamide (PEA) ≥99%

oil solubility, water solubility, fine powder, general white fine powder

Palmitoylethanolamide (PEA) effects

  • Pain Relief
  • Brain Health and Regeneration
  • Supporting Eye Health
  • Symptoms of Depression
  • Symptoms of Multiple Sclerosis
  • Fighting the Common Cold

Dosage and Stack


Talk to your doctor before supplementing with PEA. As a dietary supplement, PEA has not been approved by the FDA for medical use.

More clinical studies would be beneficial, but limited data suggests that PEA is safe. Long-term PEA supplementation has not been linked to adverse effects in small-scale studies. PEA was used in doses of 300 mg to 1.8 g/day in clinical studies.

At least 600 mg/day may be needed to relieve nerve pain, while doses of 1.2 g/day were used for diabetic nerve pain
PEA up to 1.8 g/day was used for reducing damage to eye nerves in people with glaucoma or diabetes
For fighting the common cold, 1.2 g/day was the standard dosage

Dosage form application

  • Pure powder form without excipients for research use.
  • Tablet or capsule for prescription use

Why buy Palmitoylethanolamide (PEA) fromNootropicsorigin?

Purity over 99% with HPLC test report provided,flexible service and fast response